【摘要】 目的  通过电子胃镜检查及13C呼气试验（13C-UBT）检测，以了解幽门螺杆菌感染情况及相应的胃镜表现，为幽门螺杆菌感染引起胃肠道病变提供确切的临床诊断依据。方法  对73例有腹痛症状的患儿进行13C呼气试验（13C-UBT）检测幽门螺杆菌感染情况，并行电子胃镜检查，观察胃镜下胃肠黏膜病变情况，对幽门螺杆菌感染与胃肠黏膜病变的关系进行分析。结果  幽门螺杆菌感染的阳性率为43.84%；男性明显多于女性，学龄期组阳性率高于学龄前组。幽门螺杆菌感染引起胃肠黏膜病变以十二指肠球部溃疡占比最高，其次为结节性胃炎。结论  13C-UBT及胃镜检查应用为幽门螺杆菌感染引起胃肠道黏膜病变诊断提供确切的依据。

【Abstract】 Objective To detect Helicobacter pylori ( H. pylori) infection through 13C-urea breath test ( 13 C-UBT) and find endoscopic morphological characteristics by gastroscopy in order to offer proofs for clinical diagnosis of gastric and duodenal diseases. Methods Helicobacter pylori in 73 children with abdominal pain were detected by 13C-UBT and gastric and duodenal mucosal morphological characteristics were observed by gastroscopy, then relationship of Helicobacter pylori infection and gastric and duodenal mucosal lesions was analyzed. Results Positive rate of H. pylori infection was 43.84%. The rate in boys was higher than that in girls, school-age children was higher than that in before-school-age. The most common lesion resulted from H. pylori infection was duodenal bulb ulcer, then was nodular gastritis. Conclusion 13C-UBT and gastroscopy provide proofs for the clinical diagnosis of gastric and duodenal diseases resulted from H.pylori infection．