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中国幽门螺杆菌感染流行病学 Meta 分析

2020-07-09

概要:

【摘要】  目的  综合分析中国幽门螺杆菌(Hp)流行状况。方法  采用 Meta 分析对中国1990~2002 年发表的有关 Hp 流行病学文献进行汇总、归纳和统计学分析。 结果  共检索3 564篇文献,Hp感染在我国分布广泛, 平均感染率为58.07%, 10~ 20 岁组已达 50%以上, Hp感染呈现明显的家庭聚集性。Hp 是胃肠疾病发生的危险因素。 结论  中国为 Hp 高感染率地区, 家庭内传播可能是 Hp 感染的主要途径。Hp 感染与胃部疾病有关联性,开展 Hp 感染和相关疾病的防治意义重大。

 

【Abstract】 Objective  To understand the epidemiologic features and etiology of Helicobacter pylori (H.pylori) infection in China so as to provide evidence for the development of preventive measures on H. pylori infection and related diseases. Methods  Meta-analysis was used to evaluate the data extracted from 1990-2002 published papers on the epidemiology of H.pylori infection in China. Results  The average infection rate of H.pylori infection in China was 58.07%, with 50% in 10 to 20 year-olds. Significant intrafamilial clustering was observed. H.pylori infection was a risk factor to develop gastrointestinal disease. Conclusions  H.pylori infections in Chinese were common and extensively distributed, which might due to close contact between family members.

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