摘要  338例病人同时进行了快速尿素酶试验（简称RUT）. Warthin-Starry染色（简称W-S染色）、培养法、13C-尿素呼气试验（13C-UBT）、血清IgG、IgM等6种诊断方法中任意3种检查，以同时2种（或以上）检查方法一致的结果作为诊断幽门螺杆菌（Hp）是否存在的标准。对上述6种方法的敏感性、特异性、符合率、阳性预测值、阴性预测值分别给予评价，结果显示：RUT、W-S染色、13C-UBT三法诊断Hp的敏感性、特异性等较高，均接近或高于90%。

Background/Aims: To compare the sensitivity, specificity, accuracy, positive and negative predictive value of the most widely available tests for diagnosis of H.pylori infection, including: rapid urease test (RUT), Warthin-Starry stain (W-S stain), culture, 13C-urea breath test (13C-UBT), serum immunoglobulin (Ig)G and IgM antibodies. Methods: 338 patients were tested for H.pylori infection by three of the above six tests. The infection atatus for each patient was established by a concordance of two or more than two test results. Results and Condusions: RUT. W-S stain and 13C-UBT have the better sensitivity and specificity, they are: URT: 91.0%. 83.3%: W-S stari: 88.9%, 93.5%; 13C-UBT: 98.0%, 90.7%. The sensitivity and specificity of RUT combined with W-S stain are better than that of RUT or W-S stain used alone (P<0.05).