【摘要】目的  综合分析并探讨幽门螺杆菌感染情况。方法  运用Meta分析方法对幽门螺杆 菌性别间和家庭聚集的研究进行综合定量分析。结果  性别间幽门螺杆菌感染率有细微差别（95% CI：0.057 9~0.096 3)父母均阳性子女幽门螺杆菌感染率较父母均阴性者为高（95%C/： 0. 337 8～0.504 2)结论幽门螺杆菌感染率存在性别差异和家庭聚集现象，幽门螺杆菌流行病学研究涉及 很多方面，但均缺乏足够调查和证据，尚需进一步研究。
【关键词】  幽门螺杆菌；性别；家庭聚集；Meta分析

Meta-analysis on Helicobacter pylori infection between sex and in family assembles WAN Yi*， XU Yong-yong， XUE Fu-bo, FAN Dai-ming. *Department of Health Statistics， The Fourth Military Medical University， Xi’ an 710032 China
【Abstract】 Objective  To understand and analyze the infection situation of Helicobacter pylori (H . pylori).  Methods  Extensively reviewing Chinese literature collecting the related with electronic documents in combination with manual retrieve and using Met - analysis to do a quantitive analysis. Results Slight difference in the infection rate of H. pylori between men and women (95% CI： 0.057 9-0.0963) was noticed. The infection rate of H. pylori in children whose parent was positive with infection of this bacteria was higher than that of children whose parent was negative (95% CI：0.3378- 0.5042) Conclusion The in feetion rate of H. pylori showed gender difference with nature of family aggregation. Epidemiological studies of H. pylori was comprehansive and involved many aspects. Further investigation needs to be focused on infection rate and other risk factors.
【Key words】 Helicobacter pylori; Sex; Family assembles; Meta-analysis