摘要：[目的]探讨启东市1972~2011年胃癌发病率变化趋势。[方法]基于启东市1972~2011年癌症发病登记数据库，对胃癌发病率作性别、年龄别、时间趋势分析，计算指标包括粗发病率、中国人口标化率（中标率）、世界人口标化率（世标率）、35~64岁截缩率、0~74岁累积率、累积风险、变化百分比（PC)及年均变化百分比(APC)等。[结果]1972~2011年启东胃癌发病15401例（男性9804例，女性5597例），粗发病率为34.26/10万，占全部癌症发病的16.60%，位居癌症发病第2位。中标率和世标率分别为16.25/10万和25.59/10万；35~64岁截缩发病率为40.03/10万；0~74岁累积发病率为3.15%，累积风险为3.10%。40年间胃癌发病的粗率、中标率和世标率的变化百分比（PC)分别为+21.90%、-55.32%与-51.20%，年均变化百分比（APC)分别为+0.49%、-2.12%、-2.06%。各时期胃癌发病率显示25~74岁各年龄组的发病率有下降趋势。年龄一出生队列方法分析显示，25~79岁各年龄组出生队列发病率有下降趋势。[结论]启东胃癌40年粗发病率总体维持在较高水平，但标化发病率已呈下降趋势。启东人群中胃癌的进一步下降，是可以预期的。
关键词：胃癌；发病率；流行病学；启东
中图分类号：R735.2文献标识码：A 文章编号：1004-0242(2014)08-0642-06
doi:10.11735/j.issn.l004-0242.2014.08.A004

Abstract：[Purpose] To investigate the incidence trend of stomach cancer from 1972 to 2011 in Qidong.[Methods] The cancer registration data of 1972~2011 were collected and analyzed for the incidence of stomach cancer by gender，age，and time trend. Crude incidence，age-standardized in¬cidence by Chinese standard population (ASR China) and by world standard population (ASR world)，truncated rate (35~64 age years old)，cumulative rate (0~74 age years old)，cumulative risk， percentage change (PC)，annual percentage change (APC)，incidence by period and birth-cohort were calculated.[Results] The new stomach cancer cases were 15401(male 9804,female 5597) from 1972 to 2011，accounted for 16.60% of the total cancer incidence，ranked 2nd. The crude incidence，ASR China and ASR world were 34.26/105,16.25/105 and 25.59/105,respectively. Trun¬cated rate (35~64 age years old)，cumulative rate (0~74 age years old) and cumulative risk were 40.03/105,3.15% and 3.10%，respectively. During the forty years period，the PCs of crude inci¬dence， ASR China and ASR world of stomach cancer were +21.90%，-55.32% and -51.20%，and the APCs，+0.49%，-2.12% and -2.06%，respectively. Age-specific incidence rates by period de¬ceased with age in people among 25~74 years， and birth-cohort incidence showed down trends a¬mong 25~79 years.[Conclusion] The incidence of stomach cancer during 1972~2011 in Qidong maintained at a higher level，but the age-standardized rates were descending. The further tendency of falling in stomach cancer could be anticipated.
Key words:stomach cancer；incidence；epidemiology；Qidong