
亚洲人群酒渣鼻与幽门螺杆菌感染关系的Meta分析
概要:
摘要:目的 探讨亚洲人群酒渣鼻与幽门螺杆菌(Hp)感染的关系。方法 用计算机检索CNKI、万方数据库、维普数据库、Pubmed、Embase等数据库,纳入关于亚洲人群幽门螺杆菌感染与酒渣鼻关系的病例对照研究。运用Stata11.0软件对文献实验数据进行Meta分析,计算比值比(OR),同时进行敏感性分析、亚组分析和Meta回归分析评估异质性来源,Begg’s Test和Egger’s Test评价发表偏倚。结果 亚洲人群中酒渣鼻患者幽门螺杆菌感染率(77.7%)明显高于健康人群(40.0%),OR=5.82,95%CI为(3.71~9.15),P=0.000。结论 幽门螺杆菌感染在酒渣鼻的发病中可能有一定的作用。
Abstract: Objective To investigate the association between acne rosacea and the infection of Helicobacter pylori (Hp). Methods The associated case-control researches of Asia's acne rosacea and the infection of Hp were retrieved in the CNKI, Wan Fang Databases, the Chinese Science & Technology Journal Database (VIP) and Pubmed, and Meta-analysis on the experimental data by calculating the odds ratio was performed using Embase Stata 11.0 software.Sensitivity analysis, subgroup analysis and Meta-regression analysis were taken to evaluate the sources of heterogeneity. Begg’s Test and Egger’s Test were used to evaluate publication bias. Results Infection rate of Hp in Asian patients with rosacea (77.7%) is significantly higher than healthy people (40.0%), OR=5.82, 95% CI is (3.71-9.15), P=0.000. Conclusion Helicobacter pylori infection may have certain effect in the pathogenesis of rosacea.


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