
缺铁性贫血与幽门螺杆菌感染的相关性研究
概要:
摘要:目的 探讨缺铁性贫血与幽门螺杆菌(Hp)感染的相关性,为临床治疗提供参考依据。方法 选取2013年5月-2014年12月于医院诊治的缺铁性贫血联合Hp感染阳性患者100例,随机分为对照组及观察组,每组各50例;对照组给予铁剂治疗,观察组给予铁剂联合抗Hp治疗,观察两组患者治疗后效果,数据采用SPSS 19.0软件进行统计分析。结果 观察组患者治疗总有效率为92.00%,显著高于对照组的80.00%,差异有统计学意义(P<0.05);经治疗后,对照组及观察组患者临床指标与治疗前相比均显著升高;观察组升高幅度优于对照组,差异均有统计学意义(P<0.05)。结论 给予缺铁性贫血伴有幽门螺杆菌感染阳性患者铁剂加抗幽门螺杆菌治疗,可以显著提高临床疗效,进一步提示了Hp感染与缺铁性贫血之间存在相关性,此治疗手段疗效显著,值得临床推广及应用。
Abstract: OBJECTIVE To investigate correlation between iron deficiency anemia and Helicobacter pylori (HP) in-fection, and provide an effective method for clinical treatment. METHODS Totally 100patients with iron deficiency anemia and HP infection treated from May 2013to Dec.2014in Lin’an People′s Hospital were randomly divided into a control group and observation group , and each group had 50cases.Control group was given iron treatment, and observation group was given iron therapy combined with anti-Hptherapy. Curative effects were observed in both groups and data were statistically analyzed with SPSS 19.0software.RESULTS Total effective rate of observation group was 92% , significantly higher than the control group (80.00%) (P<0.05). After treatment, the Hp infection rate of control group and observation group were significantly decreased; the decrease rate of observation group was significantly higher than control group (P<0.05). CONCLUSION To give patients with iron deficiency anemia and positive HP infection with iron and anti HP therapy can significantly improve clinical efficacy, which implicates the correlation between HP infection and iron deficiency anemia. The treatment effect is significant, therefore this method is worthy of clinical popularization and application.


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