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联用免疫疗法和根除幽门螺杆菌疗法治疗儿童特发性血小板减少性紫癜的效果研究

2020-07-09

概要:

【摘要】目的:探讨分析联用免疫疗法和根除幽门螺杆菌疗法治疗儿童特发性血小板减少性紫癜的临床效果。方法:选取2013年5月~2014年8月间我院收治的患有特发性血小板减少性紫癜的患儿200例作为研究对象,采用随机数字表法将其分为对照组(100例)和研究组(100例),采用免疫疗法为对照组患儿进行治疗,联用免疫疗法和根除幽门螺杆菌疗法为研究组患儿进行治疗,观察对比两组患儿的临床疗效,并将对比的结果及两组患儿的临床资料进行回顾性的分析。结果:研究组患儿治疗的总有效率为97.00%,对照组患儿治疗的总有效率为83.00%,研究组患儿的临床疗效明显优于对照组患儿,差异显著(P<0.05),具有统计学意义。经检测,连续治疗3个月后,研究组患儿的血小板数目为(114.20±4.52)×109L-1,对照组患儿的血小板数目为(59.84±7.28)×109L-1,研究组患儿的血小板数目明显高于对照组患儿,差异显著(P<0.05),具有统计学意义。结论:联用免疫疗法和根除幽门螺杆菌疗法治疗儿童特发性血小板减少性紫癜的临床效果显著,值得在临床上推广应用。

 

【Abstract】 Objective: To investigate the clinical significance of Helicobacter pylori in children with idiopathic thrombocytopenic purpura in. METHODS: The study group of children given immunity Helicobacter pylori eradication therapy combined with the control group were treated with immune therapy alone, compared two groups of children on platelets and clinical efficacy. Results: After treatment, 200 cases of thrombocytopenia in children with idiopathic purpura, a study group of patients with the disease in children can be improved up to 97.00% , higher, at 3 months after treatment, examination, study platelet count was significantly more than the control group of patients, the clinical effect is more significant (P<0.05). Conclusion: Helicobacter pylori and children with idiopathic thrombocytopenic purpura is closely linked, using immunohistochemistry combined Helicobacter pylori eradication therapy, the ideal clinical results, platelet rehabilitation of children with idiopathic thrombocytopenic purpura has a positive meaning, worthy.

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